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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1675768Generated: October 31, 2026

Dichloromethane → HCID 18449380, compound

https://huagongshe.com/reaction/1675768

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDichloromethaneHCID 6344—
ReactantHCID 86619735HCID 86619735—
SolventTrifluoroacetic acidHCID 6422—
ProductHCID 18449380HCID 18449380—

Reaction Steps

(±)-tert-Butyl {3-[4-(methylsulfinyl)-1,3-thiazol-2-yl]-2-oxo-2,3-dihydro-1H-benzimidazol-1-yl}acetate from Step D (100 mg, 0.254 mmol) was dissolved in CF3CO2H (3 mL) and CH2Cl2 (3 mL) and the mixture was stirred at ambient temperature for 3 h, then concentrated in vacuo to give the title compound. MS: m/z=338 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08003792B2
Source datasetuspto-grants-2011_08
ORD IDord-1f5810060d984d66af8f7d995a8fb42c
Source noteuspto-grants-2011_08