HCID 67353084, compound → HCID 58653668, compound

HRID 1676016Notes

Reaction equation

HRID 1676016 reaction equation
[NH2:1][C:2]1[CH:17]=[CH:16][C:5]2[N:6]([CH:9]([CH3:15])[CH2:10][C:11]([O:13]C)=[O:12])[CH:7]=[N:8][C:4]=2[CH:3]=1>Cl>[NH2:1][C:2]1[CH:17]=[CH:16][C:5]2[N:6]([CH:9]([CH3:15])[CH2:10][C:11]([OH:13])=[O:12])[CH:7]=[N:8][C:4]=2[CH:3]=1

Participants

3

Reactant 1

HCID 67353084HCID 67353084, compound

Product 1

HCID 58653668HCID 58653668, compound

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Procedure

A solution of methyl 3-(5-amino-1H-benzimidazol-1-yl)butanoate (91 mg, 390 μmol) in hydrochloric acid (5 mL of a 5N solution) was stirred at room temperature for 163 hours. The solution was then evaporated in vacuo to afford the title compound, [LCMS (Method A, Mobile Phase II) RT=1.54 min, MH+ 220].

Workup

  1. customThe solution was then evaporated in vacuo

Sources & evidence

ORD record
ord-072caa230e2247c3967fae68388538c2
Source dataset
uspto-grants-2011_08
Patent number
US08003806B2

Reaction notes

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