HCID 67352396, compound → HCID 58653658, compound

HRID 1676017Notes

Reaction equation

HRID 1676017 reaction equation
[NH2:1][C:2]1[CH:3]=[CH:4][C:5]2[N:9]=[CH:8][N:7]([CH:10]([CH3:16])[CH2:11][C:12]([O:14]C)=[O:13])[C:6]=2[CH:17]=1>Cl>[NH2:1][C:2]1[CH:3]=[CH:4][C:5]2[N:9]=[CH:8][N:7]([CH:10]([CH3:16])[CH2:11][C:12]([OH:14])=[O:13])[C:6]=2[CH:17]=1

Participants

3

Reactant 1

HCID 67352396HCID 67352396, compound

Product 1

HCID 58653658HCID 58653658, compound

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Procedure

A solution of methyl 3-(6-amino-1H-benzimidazol-1-yl)butanoate (78 mg, 334 μmol) in hydrochloric acid (5 mL of a 5N solution) was stirred at room temperature for 163 hours. The solution was then evaporated in vacuo to afford the title compound, [LCMS (Method A, Mobile Phase II) RT=1.53 min, MH+ 220].

Workup

  1. customThe solution was then evaporated in vacuo

Sources & evidence

ORD record
ord-4608877093ec4d6e8206367432015215
Source dataset
uspto-grants-2011_08
Patent number
US08003806B2

Reaction notes

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