HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 58653632, compound → HCID 11511224, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 58653632 | HCID 58653632 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Product | HCID 11511224 | HCID 11511224 | — |
Reaction Steps
A solution of methyl 3-phenyl-3-(4-{4-[(1,4,5,6-tetrahydro-2-pyrimidinylamino)carbonyl]-1-piperidinyl}-1H-benzimidazol-1-yl)propanoate (17 mg, 24 μmol) in hydrochloric acid (10 mL of a 5N solution) was stirred at room temperature for 48 hours. The solution was evaporated in vacuo, and the residue purified by RP-HPLC to afford the title compound, [LCMS (Method A, Mobile Phase II) RT=3.5 min, MH+ 475].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08003806B2 |
| Source dataset | uspto-grants-2011_08 |
| ORD ID | ord-33ad9f132e3b4a46b31881066cea25e5 |
| Source note | uspto-grants-2011_08 |