HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetonitrile → 4-Isobutyl-3,5-dimethylthiophene-2-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetonitrile | HCID 6342 | — |
| Reactant | 4-Isobutyl-5-methylthiophene-2-carboxylic acid | HCID 59497874 | — |
| Product | 4-Isobutyl-3,5-dimethylthiophene-2-carboxylic acid | HCID 59497866 | — |
Reaction Steps
4-Isobutyl-3,5-dimethyl-thiophene-2-carboxylic acid is prepared from 4-isobutyl-5-methyl-thiophene-2-carboxylic acid in analogy to Intermediate A2; LC-MS: tR=0.97 min, [M+1+CH3CN]=254.26; 1H NMR (CDCl3): δ 2.46 (s, 3H), 2.39 (s, 3H), 2.36 (d, J=7.0 Hz, 2H), 1.78 (hept, J=7.0 Hz, 1H), 0.91 (d, J=7.0 Hz, 6H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08003800B2 |
| Source dataset | uspto-grants-2011_08 |
| ORD ID | ord-6437473ab1704749b9e96aa955cdd9b7 |
| Source note | uspto-grants-2011_08 |