Potassium Carbonate → HCID 10942670, compound

HRID 1676132Notes

Reaction equation

HRID 1676132 reaction equation
[C:1]([CH2:4][C:5](=[O:7])[CH3:6])(=[O:3])[CH3:2].C([O-])([O-])=O.[K+].[K+].Br[CH2:15][C:16]([CH3:18])=[CH2:17]>CC(C)=O>[CH3:17][C:16](=[CH2:15])[CH2:18][CH:4]([C:5](=[O:7])[CH3:6])[C:1](=[O:3])[CH3:2]

Participants

5

Reactant 3

HCID 11430Potassium CarbonateHCID 31261AcetylacetoneHCID 3577853-Bromo-2-methyl-1-propene

Product 1

HCID 10942670HCID 10942670, compoundYield 64.3%

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Conditions

Temperature
50 °C

Procedure

A mixture of acetylacetone (2.5 g, 25 mmol), K2CO3 (3.45 g, 25 mmol) and 3-bromo-2-methylpropene (2.5 mL, 25 mmol) in acetone (80 mL) is stirred at 50° C. for 3 days. The mixture is filtered, the filtercake washed with few acetone and the filtrate evaporated to give 2.48 g of 3-(2-methyl-allyl)-pentane-2,4-dione as a dark oil that is used without further purification in subsequent steps; LC-MS: tR=0.87 min, [M+1]+=155.26.

Workup

  1. filtrationThe mixture is filtered
  2. washthe filtercake washed with few acetone
  3. customthe filtrate evaporated

Sources & evidence

ORD record
ord-0105c6d8811940d79370c6cb073f3986
Source dataset
uspto-grants-2011_08
Patent number
US08003800B2

Reaction notes

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