反应详情

Prepared from 3-fluoro-4-(2-iodothieno[3,2-b]pyridin-7-yloxy)benzenamine (Example 6, Step A; 0.300 g, 0.777 mmol) and 4-(methylcarbamoyl)phenylboronic acid (0.174 g, 0.971 mmol) according to the procedure described for Example 94, Step A. Purified by trituration from hot MeOH to obtain the product (210 mg, 96%) as a brown solid. LRMS (APCI pos) m/e 394 (M+1).

1. customPurified by trituration from hot MeOH