HCID 24772584, compound → HCID 24772585, compound

Participants

Reaction Steps

2-Benzyloxy-N-[4-(2-benzyloxy-acetylamino)-phenyl]-acetamide 3 (10 grams, 24.75 mmol) is dissolved in methanol (100 mL) in a pressure vessel. Pd/C (10%, 3 grams) is added, and the mixture is stirred under an atmosphere of hydrogen (4 Kg) for 5 hours. The catalyst is removed by filtration, and the methanol is distilled off. The crude 4 can be purified in a suitable solvent.

Provenance & Evidence