HCID 24772586, compound → HCID 24772587, compound

Participants

Reaction Steps

4-(2-Benzyloxy-acetylamino)-benzoic acid methoxycarbonylmethyl ester 7 (10 grams, 28.98 mmol) is dissolved in methanol (100 mL) in a pressure vessel. Pd/C (10%, 3 grams) is added, and the mixture is stirred under an atmosphere of hydrogen (4 Kg) for 5 hours. The catalyst is removed by filtration, and the methanol is distilled off. The crude 8 can be purified in a suitable solvent.

Provenance & Evidence