Sodium Chloride → HCID 58895262, compound

HRID 1676864Notes

Reaction equation

Cl[C:2]([O:4][CH2:5][CH3:6])=[O:3].[CH3:7][C:8]([CH:10]1[CH2:15][CH2:14][C:13]([CH2:16][NH2:17])=[CH:12][CH2:11]1)=[CH2:9].C(N(CC)CC)C.[Cl-].[Na+]>>[CH3:9][C:8]([CH:10]1[CH2:15][CH2:14][C:13]([CH2:16][NH:17][C:2](=[O:3])[O:4][CH2:5][CH3:6])=[CH:12][CH2:11]1)=[CH2:7]

Participants

Reactant 4

HCID 5234Sodium Chloride

HCID 8471Triethylamine

HCID 10928Ethyl chloroformate

HCID 10374618HCID 10374618, compound

Product 1

HCID 58895262HCID 58895262, compound

Procedure

Ethyl chloroformate 1.1 eq, [4-(1-methylethenyl)-1-cyclohexen-1-yl]methylamine 1.0 eq, triethylamine 1.3 eq, quench with 10% sodium chloride solution, yield=37%.

Sources & evidence

ORD record: ord-100a4032a51048b4974e900cd8bf9613
Source dataset: uspto-grants-2011_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08007849B2

Reaction notes

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