Isoquinoline, 1-chloro- → 2-(RS)-(Isoquinolin-1-ylaminomethyl)-piperidine-1-carboxylic acid tert butyl ester

HRID 167689Notes

Reaction equation

HRID 167689 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([CH2:14][NH2:15])[CH2:10][CH2:11][CH2:12][CH2:13]1.[Cl:16][c:17]1[n:18][cH:19][cH:20][c:21]2[cH:22][cH:23][cH:24][cH:25][c:26]12>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([CH2:14][NH:15][c:17]2[n:18][cH:19][cH:20][c:21]3[cH:22][cH:23][cH:24][cH:25][c:26]23)[CH2:10][CH2:11][CH2:12][CH2:13]1

Participants

3

Reactant 2

HCID 140539Isoquinoline, 1-chloro-HCID 2756482tert-Butyl 2-(aminomethyl)piperidine-1-carboxylate

Product 1

HCID 865936692-(RS)-(Isoquinolin-1-ylaminomethyl)-piperidine-1-carboxylic acid tert butyl ester

Sources & evidence

ORD record
ord-bb16d55b0fe84ddf8703e659c68fb2aa
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

Loading…