Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1676930Generated: October 25, 2026

Furosemide → Benzyl 5-aminosulfonyl-4-chloro-2-[(2-furanylmethyl)amino]benzoate

https://huagongshe.com/reaction/1676930

Reaction equation

Participants

RoleNameHCIDCharge
ReactantFurosemideHCID 3440—
ReactantBenzyl ChlorideHCID 7503—
SolventDimethylformamideHCID 6228—
ProductBenzyl 5-aminosulfonyl-4-chloro-2-[(2-furanylmethyl)amino]benzoateHCID 11697463—

Reaction Steps

In a similar manner to Example 3, furosemide can be reacted with benzyl chloride in DMF to yield benzyl 5-aminosulfonyl-4-chloro-2-[(2-furanylmethyl)amino]benzoate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08008283B2
Source datasetuspto-grants-2011_08
ORD IDord-0728766472e54d80aa3b9252f0cc9871
Source noteuspto-grants-2011_08