HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → N-(3-piperidin-1-yl-propyl)-terephthalamic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Piperidine-1-propylamine | HCID 19049 | — |
| Reactant | Terephthalic acid monomethylester chloride | HCID 53442854 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | N-(3-piperidin-1-yl-propyl)-terephthalamic acid methyl ester | HCID 11673899 | — |
Reaction Steps
For example, terephtalic acid monomethyl ester chloride is treated with an alkylamine, in this case 3-piperidinopropylamine, and triethylamine, in a suitable solvent such as dichloromethane at ambient temperature for 1-12 hours to provide the desired amide, N-(3-piperidin-1-yl-propyl)-terephthalamic acid methyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08008296B2 |
| Source dataset | uspto-grants-2011_08 |
| ORD ID | ord-df38345f8b1744cdb3ea3a95ffbb197f |
| Source note | uspto-grants-2011_08 |