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HRID1676953

反应详情

EQUATION

反应方程式

HRID 1676953 的结构方程式

REACTANTS

反应物

2
反应SMILES：O=C(O)c1ccc(S(=O)(=O)Cl)cc1
HCID82385

Benzoic acid, 4-(chlorosulfonyl)-

C7H5ClO4S

反应SMILES：CS(=O)(=O)C1CCNC1
HCID3419356

3-(methylsulfonyl)pyrrolidine

C5H11NO2S

PRODUCTS

产物

1
反应SMILES：CS(=O)(=O)C1CCN(S(=O)(=O)c2ccc(C(=O)O)cc2)C1
HCID67176446

4-[3-(Methanesulfonyl)pyrrolidine-1-sulfonyl]benzoic acid

C12H15NO6S2

收率 44.1%

PROCEDURE

实验过程

The title intermediate is prepared from 4-(chlorosulfonyl)benzoic acid (CAS 10130-89-9) (375 mg, 1.7 mmol) and 3-(methylsulfonyl)pyrrolidine (CAS 433980-62-2) (343 mg, 2.3 mmol) in a manner substantially similar to Procedure F to provide 250 mg (44%) of the title compound. MS (ES−) 332.0 (M−H)−.