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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1676987Generated: October 30, 2026

Morpholine → HCID 10472353, compound

https://huagongshe.com/reaction/1676987

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMorpholineHCID 8083—
ReactantMethylamine hydrochlorideHCID 6364545—
Reactantethyl 5-chloro-3-(chlorosulfonyl)-1-(phenylsulfonyl)-1H-indole-2-carboxylateHCID 22401482—
ReactantHCID 86601813HCID 86601813—
SolventTriethylamineHCID 8471—
ProductHCID 10472353HCID 10472353—

Reaction Steps

Following the procedures described in Steps D and E of Example 1, replacing in Step D ethyl 5-chloro-3-(chlorosulfonyl)-1-(phenylsulfonyl)-1H-indole-2-carboxylate with ethyl 3-(chlorosulfonyl)-5-methoxy-1-(phenylsulfonyl)-1H-indole-2-carboxylate, and methylamine hydrochloride and triethylamine with morpholine, the title compound was obtained. HRMS (ES) exact mass calculated for C14H18N3O5S (M+H+): 340.0962. Found 340.0960.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08008295B2
Source datasetuspto-grants-2011_08
ORD IDord-8bc8b52537384ec7bd96b4627b4ad87c
Source noteuspto-grants-2011_08