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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1676991Generated: November 1, 2026

4-Methylsulfonylbenzylamine hydrochloride → HCID 10074131, compound

https://huagongshe.com/reaction/1676991

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Methylsulfonylbenzylamine hydrochlorideHCID 2729269—
ReactantMethylamine hydrochlorideHCID 6364545—
Reactantethyl 5-chloro-3-(chlorosulfonyl)-1-(phenylsulfonyl)-1H-indole-2-carboxylateHCID 22401482—
Reactantethyl 3-(chlorosulfonyl)-5-bromo-1-(phenylsulfonyl)-1H-indole-2-carboxylateHCID 86592455—
ProductHCID 10074131HCID 10074131—

Reaction Steps

Following the procedures described in Steps D and E of Example 1, replacing in Step D ethyl 5-chloro-3-(chlorosulfonyl)-1-(phenylsulfonyl)-1H-indole-2-carboxylate with ethyl 5-bromo-3-(chlorosulfonyl)-1-(phenylsulfonyl)-1H-indole-2-carboxylate, and methylamine hydrochloride with 4-(methylsulfonyl)benzylamine hydrochloride, the title compound was obtained. HRMS (ES) exact mass calculated for C17H17BrN3O5S2 (M+H+): 485.9788. Found 485.9784.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08008295B2
Source datasetuspto-grants-2011_08
ORD IDord-46c5d88bb17a4745ba0b78f5f9c3f090
Source noteuspto-grants-2011_08