反应详情

Following the procedures described in Steps D and E of Example 1, replacing in Step D ethyl 5-chloro-3-(chlorosulfonyl)-1-(phenylsulfonyl)-1H-indole-2-carboxylate with ethyl 5-iodo-3-(chlorosulfonyl)-1-(phenylsulfonyl)-1H-indole-2-carboxylate, and methylamine hydrochloride with (±)-1-tetrahydro-2H-pyran-2-ylmethanamine, the title compound was obtained. Proton NMR for the product was consistent with the titled compound. ESI+ MS: 463.95 [M+H]+.