HCID 67371255, compound → HCID 67372881, compound

Participants

Reaction Steps

20% palladium hydroxide on carbon (100 mg, 50% water contain) was added to an ethanol (7 mL) solution of 1-[(2R,5S)-1-benzyl-5-(3,4,5-trifluorophenyl)pyrrolidine-2-yl]cyclopropanol (600 mg). Under a hydrogen atmosphere, stirring was continued for 3 hours. The resultant was filtered on celite, and by removing the solvent under a vacuum, the title compound (440 mg) was obtained. The physical property values are as follows.

Provenance & Evidence