HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Methylpiperazine → HCID 57571698, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Methylpiperazine | HCID 53167 | — |
| Reactant | 2-(4-Chlorophenyl)ethylamine | HCID 67430 | — |
| Reactant | Methyl 6-chloro-4-(trifluoromethyl)nicotinate | HCID 2775340 | — |
| Product | HCID 57571698 | HCID 57571698 | — |
Reaction Steps
In analogy to example 1 methyl 6-chloro-4-(trifluoromethyl)nicotinate was reacted with N-methylpiperazine and then, using 4-chlorophenethylamine in the coupling step, converted to N-[2-(4-chloro-phenyl)-ethyl]-6-(4-methyl-piperazin-1-yl)-4-trifluoro-methyl-nicotinamide. Off-white solid. MS (ISP): 427.2 ([M+H]+)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08008305B2 |
| Source dataset | uspto-grants-2011_08 |
| ORD ID | ord-483ecd1767654629a8a7c51d2431efd5 |
| Source note | uspto-grants-2011_08 |