Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1677192Generated: October 31, 2026

Prolinol, (R)- → HCID 57980097, compound

https://huagongshe.com/reaction/1677192

Reaction equation

Participants

RoleNameHCIDCharge
ReactantProlinol, (R)-HCID 2724541—
Reactant4'-(Trifluoromethyl)-[1,1'-biphenyl]-4-carboxylic acidHCID 2782719—
ReactantLithiumHCID 3028194—
ProductHCID 57980097HCID 57980097—

Reaction Steps

The title compound is prepared in a manner substantially analogous to Procedure B′ from 4′-trifluoromethyl-biphenyl-4-carboxylic acid, lithium salt using (R)-2-pyrrolidine methanol as the amine. MS (ES+) 350.2

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08008301B2
Source datasetuspto-grants-2011_08
ORD IDord-55ec914f5b5d4d6aa93d3ee10fb51cf6
Source noteuspto-grants-2011_08