Trifluoroacetic acid → HCID 59322874, compound

Participants

Reaction Steps

Method (ii)—Removing Boc protection by Preparing Trifluoroacetic salt: The trifluoroacetic salt of 2-{2-[(2-aminoethyl)methylamino]ethyl}-6-methoxy-1,2-dihydro-3H-dibenzo[de,h]isoquinoline-1,3-dione was prepared by stirring (2-{[2-(6-Methoxy-1,3-dioxo-1H,3H-dibenzo[de,h]isoquinolin-2-yl)-ethyl]-methyl-amino}-ethyl)-carbamic acid tert-butyl ester with 50% trifluoroacetic acid in DCM for 40 minutes. The reaction was quantitative.

Provenance & Evidence