HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
3-(Pyrrolidino)phenylboronic acid → (1-Methyl-cycloheptyl)-[2-(3-pyrrolidin-1-yl-phenyl)-5H-pyrrolo[2,3-b]pyrazin-7-yl]-methanone
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 3-(Pyrrolidino)phenylboronic acid | HCID 4192669 | — |
| Edukt | (2-bromo-5H-pyrrolo[2,3-b]pyrazin-7-yl)-(1-methyl-cycloheptyl)-methanone | HCID 44199844 | — |
| Produkt | (1-Methyl-cycloheptyl)-[2-(3-pyrrolidin-1-yl-phenyl)-5H-pyrrolo[2,3-b]pyrazin-7-yl]-methanone | HCID 59540711 | — |
Reaktionsschritte
(1-Methyl-cycloheptyl)-[2-(3-pyrrolidin-1-yl-phenyl)-5H-pyrrolo[2,3-b]pyrazin-7-yl]-methanone was prepared starting from (2-bromo-5H-pyrrolo[2,3-b]pyrazin-7-yl)-(1-methyl-cycloheptyl)-methanone and 3-(1-pyrrolidinyl)phenylboronic acid following general procedures as described in these Examples. MP 192-193° C., M+H=403.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08008298B2 |
| Quelldatensatz | uspto-grants-2011_08 |
| ORD ID | ord-de8046b25154432c980612f225f67a70 |
| Quellennotiz | uspto-grants-2011_08 |