Thionyl Chloride → HCID 59540922, compound

HRID 1677488Notes

Reaction equation

HRID 1677488 reaction equation
[CH2:1]([O:8][CH:9]1[CH2:14][CH2:13][C:12]([CH3:18])([C:15](O)=[O:16])[CH2:11][CH2:10]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.S(Cl)([Cl:21])=O>>[CH2:1]([O:8][CH:9]1[CH2:14][CH2:13][C:12]([CH3:18])([C:15]([Cl:21])=[O:16])[CH2:11][CH2:10]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 59540962HCID 59540962, compound

Product 1

HCID 59540922HCID 59540922, compoundYield 99%

Procedure

A solution of 4-benzyloxy-1-methyl-cyclohexanecarboxylic acid (1.71 g, 6.89 mmol) in thionyl chloride (10 ml) was refluxed for 2 hours. The reaction mixture was concentrated on high vacuum giving 1.84 g (99%) of 4-benzyloxy-1-methyl-cyclohexanecarbonyl chloride as a yellow oil.

Workup

  1. concentrationThe reaction mixture was concentrated on high vacuum

Sources & evidence

ORD record
ord-27f50381b43b4720a59543a5ccda5790
Source dataset
uspto-grants-2011_08
Patent number
US08008298B2

Reaction notes

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