HCID 67345820, compound → HCID 59540932, compound

Participants

Reaction Steps

1-{2-[3-(3-Methoxymethyl-3-methyl-pyrrolidin-1-yl)-phenyl]-5H-pyrrolo[2,3-b]pyrazin-7-yl}-2,2-dimethyl-propan-1-one was prepared following the same procedure using 1-[2-[3-(3-Methoxymethyl-3-methyl-pyrrolidin-1-yl)-phenyl]-5-(2-trimethylsilanyl-ethoxymethyl)-5H-pyrrolo[2,3-b]pyrazin-7-yl]-2,2-dimethyl-propan-1-one as starting material. The product was obtained in 50% yield by SiO2 chromatography (DCM/MeOH 0-5% MeOH).

Provenance & Evidence