Oxalyl chloride → HCID 59540530, compound

HRID 1677520Notes

Reaction equation

HRID 1677520 reaction equation
C(Cl)(=O)C([Cl:4])=O.[C:7]([CH2:9][CH2:10][CH2:11][C:12]([CH3:17])([CH3:16])[C:13](O)=[O:14])#[N:8]>ClCCl>[C:7]([CH2:9][CH2:10][CH2:11][C:12]([CH3:17])([CH3:16])[C:13]([Cl:4])=[O:14])#[N:8]

Participants

4

Reactant 2

HCID 65578Oxalyl chlorideHCID 19875375HCID 19875375, compound

Product 1

HCID 59540530HCID 59540530, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Oxalyl chloride (0.39 mL, 4.5 mmol) was added to a 0-5° C. solution of 5-cyano-2,2-dimethyl-pentanoic acid (0.462 g, 2.98 mmol) in 3 mL of dichloromethane, and the mixture was stirred for 3 h then concentrated to afford crude 5-cyano-2,2-dimethyl-pentanoyl chloride as a yellow oil, which was immediately used in the next step.

Workup

  1. concentrationthen concentrated

Sources & evidence

ORD record
ord-4c02797e9da34cb1a70931d71d7f5c14
Source dataset
uspto-grants-2011_08
Patent number
US08008298B2

Reaction notes

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