Hydrazine hydrate (1:1) → HCID 178509212, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 1.2 g of 2-hydroxy-4-methoxynicotinonitrile and 30 mL of hydrazine hydrate is maintained at 140° C. for 18 hours in a bomb. The reaction medium is then evaporated to dryness. The residue is taken up in ethyl ether, and the resulting suspension is filtered. 1.1 g of 3-amino-1H-pyrazolo[4,3-c]pyrid-4-ol are obtained in the form of a grey solid.

Provenance & Evidence