HCID 67329712, compound → 1-[4-(3-amino-1H-pyrazolo[3,4-b]pyrid-4-yl)phenyl]-3-(2-ethoxy-5-trifluoromethylphenyl)urea

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Reaction Steps

1-(2-Ethoxy-5-trifluoromethylphenyl)-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]urea is coupled, by Suzuki reaction, with 4-iodo-1H-pyrazolo[3,4-b]pyrid-3-ylamine according to the preparation of Example 6. A yellow powder of 1-[4-(3-amino-1H-pyrazolo[3,4-b]pyrid-4-yl)phenyl]-3-(2-ethoxy-5-trifluoromethylphenyl)urea is obtained, the characteristics of which are as follows:

Provenance & Evidence