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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1677756생성일: 2026년 10월 25일

1-Chloro-4-(trifluoromethylsulfonyl)benzene → (3R)-3-methyl-1-{4-[(trifluoromethyl)sulfonyl]phenyl}piperazine

https://huagongshe.com/reaction/1677756

반응식

참여 물질

역할이름HCID투입량
반응물1-Chloro-4-(trifluoromethylsulfonyl)benzeneHCID 703324—
반응물(3R)-1-[4-(Methanesulfonyl)phenyl]-3-methylpiperazineHCID 26597658—
생성물(3R)-3-methyl-1-{4-[(trifluoromethyl)sulfonyl]phenyl}piperazineHCID 11580385—

반응 단계

The title compound was prepared following the procedure of Intermediate 26, but starting from 1-chloro-4-(trifluoromethanesulfonyl)benzene. Purification by flash chromatography (CHCl3/MeOH) gave the title compound as a pale yellow solid. M+(ESI): 309.2. HPLC (Condition A), Rt: 2.3 min (HPLC purity: 99.5%).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08008302B2
출처 데이터셋uspto-grants-2011_08
ORD IDord-1b9f2b8bc99142e7a622856de3f4818c
출처 메모uspto-grants-2011_08