Potassium Bromide → HCID 10791645, compound

HRID 1677838Notes

Reaction equation

[K+].[Br-].[CH3:3][C@@H:4]1[C:39]([CH3:41])([CH3:40])[O:38][C@:6]2([O:10][C@H:9]3[CH2:11][C@H:12]4[C@@H:17]5[CH2:18][CH2:19][C@H:20]6[CH2:25][C@H:24]([O:26][C:27]([CH3:29])=[O:28])[CH2:23][CH2:22][C@:21]6([CH3:30])[C@H:16]5[C@@H:15]([O:31]C(C)=O)[CH2:14][C@:13]4([CH3:35])[C@H:8]3[C@:7]2([OH:37])[CH3:36])[CH2:5]1>>[CH3:3][C@@H:4]1[C:39]([CH3:40])([CH3:41])[O:38][C@@:6]2([O:10][C@H:9]3[CH2:11][C@H:12]4[C@@H:17]5[CH2:18][CH2:19][C@H:20]6[CH2:25][C@H:24]([O:26][C:27]([CH3:29])=[O:28])[CH2:23][CH2:22][C@:21]6([CH3:30])[C@H:16]5[C@@H:15]([OH:31])[CH2:14][C@:13]4([CH3:35])[C@H:8]3[C@:7]2([OH:37])[CH3:36])[CH2:5]1

Participants

Reactant 2

HCID 253877Potassium Bromide

HCID 20833539HCID 20833539, compound

Product 1

HCID 10791645HCID 10791645, compound

Procedure

white solid, mp 193.5-195° C., 1H NMR (CDCl3) δ 5.01 (brs, 1H), 4.44 (dt, J=5.0, 7.5 Hz, 1H), 4.30 (brs, 1H), 2.26 (m, 1H), 2.16 (dd, J=2.5, 14.0 Hz, 1H), 2.04 (s, 3H), 1.34 (s, 3H), 1.30 (s, 3H), 1.28 (s, 3H), 1.04 (s, 3H), 0.99 (s, 3H), 0.94 (d, J=7.0 Hz, 3H); IR (KBr) 3490, 1710, 1245 cm−1; EIMS m/z 504 (M+, 2), 489 (3), 446 (16), 376 (60), 358 (100%).

Sources & evidence

ORD record: ord-992e1cffeb714efdb62e2abb2abcfca8
Source dataset: uspto-grants-2011_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08008346B2

Reaction notes

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