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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1677882Generated: October 30, 2026

(R)-2-Tosyloxypropionic acid methyl ester → methyl (2S)-2-({3',5-difluoro-4'-[(3-fluorophenyl)sulfonyl]biphenyl-2-yl}oxy)propanoate

https://huagongshe.com/reaction/1677882

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(R)-2-Tosyloxypropionic acid methyl esterHCID 12884153—
Reactant3',5-Difluoro-4'-[(3-fluorophenyl)sulfonyl]biphenyl-2-olHCID 67238560—
Productmethyl (2S)-2-({3',5-difluoro-4'-[(3-fluorophenyl)sulfonyl]biphenyl-2-yl}oxy)propanoateHCID 67239694—

Reaction Steps

The subtitle compound was prepared by the method of example 11 step (vii) using the product of step (iv) and the product of example 11 step (vi).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08008350B2
Source datasetuspto-grants-2011_08
ORD IDord-803ecde1571c423d99e499a501b14e8c
Source noteuspto-grants-2011_08