2,2,2-Trifluoroethanol → 1-(2-Methoxy-5-thiazolyl)ethanone

HRID 1678067Notes

Reaction equation

HRID 1678067 reaction equation
C(O)C(F)(F)F.FC(F)(F)[CH2:9][O:10][C:11]1[S:12][C:13]([C:16](=[O:18])[CH3:17])=[CH:14][N:15]=1>>[CH3:9][O:10][C:11]1[S:12][C:13]([C:16](=[O:18])[CH3:17])=[CH:14][N:15]=1

Participants

3

Reactant 2

HCID 64092,2,2-TrifluoroethanolHCID 58629012HCID 58629012, compound2×

Product 1

HCID 586290871-(2-Methoxy-5-thiazolyl)ethanone

Procedure

The following compound was prepared using trifluoroethanol according to the procedure used in preparing compound 192: 1-[2-(2,2,2-trifluoroethoxy)-1,3-thiazol-5-yl]ethanone (compound 204)

Workup

  1. customThe following compound was prepared

Sources & evidence

ORD record
ord-7c1b7870b0744ea3bcc8c910a17d5938
Source dataset
uspto-grants-2011_08
Patent number
US08008487B2

Reaction notes

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