Chlorosuccinimide → HCID 67372053, compound

HRID 1678129Notes

Reaction equation

[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([N:7]2[C:15]3[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=3)[CH:9]=[CH:8]2)[CH:2]=1.ClN1C(=[O:22])CCC1=O>>[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([N:7]2[C:15]3[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=3)[CH2:9][C:8]2=[O:22])[CH:2]=1

Participants

Reactant 2

HCID 31398Chlorosuccinimide

HCID 134903481-(pyridin-3-yl)-1H-indole

Product 1

HCID 67372053HCID 67372053, compoundYield 59%

Procedure

1-(pyridin-3-yl)-1H-indole is reacted with N-chlorosuccinimide as described in Example 12 to give 1-(pyridin-3-yl)-1,3-dihydroindol-2-one (59% yield) as a light brown solid.

Sources & evidence

ORD record: ord-ce3c6bb1947144f9a0573f085c419211
Source dataset: uspto-grants-2011_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08008491B2

Reaction notes

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