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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1678131Generated: November 2, 2026

Piperazine → 2-(piperazin-1-yl)-1-(pyridin-3-yl)-1H-indole-3-carboxaldehyde

https://huagongshe.com/reaction/1678131

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPiperazineHCID 4837—
ReactantHCID 86035953HCID 86035953—
Product2-(piperazin-1-yl)-1-(pyridin-3-yl)-1H-indole-3-carboxaldehydeHCID 1128975023%

Reaction Steps

2-chloro-1-(pyridin-3-yl)-1,3-dihydroindole-3-carboxaldehyde is reacted with piperazine as described in Example 2 to give, after flash chromatography, the title compound (23% yield).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08008491B2
Source datasetuspto-grants-2011_08
ORD IDord-69d6fb9fff614268a05ba73e674956ce
Source noteuspto-grants-2011_08