反应详情

2-Chloro-1H-indole-3-carboxaldehyde is reacted with 4-tolylboronic acid as described in Step 1 of Example 29 to afford 2-chloro-1-(4-methylphenyl)-1H-indole-3-carboxaldehyde (48% yield) as a cream solid. ESI/MS 270 (M+H), 311 [(M+1+CH3CN) adduct]: RT=3.55 min.