HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Tolylboronic acid → 2-chloro-1-(4-methylphenyl)-1H-indole-3-carboxaldehyde
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Tolylboronic acid | HCID 79799 | — |
| Edukt | 2-chloro-1H-indole-3-carbaldehyde | HCID 314791 | — |
| Produkt | 2-chloro-1-(4-methylphenyl)-1H-indole-3-carboxaldehyde | HCID 86035929 | 48% |
Reaktionsschritte
2-Chloro-1H-indole-3-carboxaldehyde is reacted with 4-tolylboronic acid as described in Step 1 of Example 29 to afford 2-chloro-1-(4-methylphenyl)-1H-indole-3-carboxaldehyde (48% yield) as a cream solid. ESI/MS 270 (M+H), 311 [(M+1+CH3CN) adduct]: RT=3.55 min.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08008491B2 |
| Quelldatensatz | uspto-grants-2011_08 |
| ORD ID | ord-de72507e15ed46008f27d43e43427229 |
| Quellennotiz | uspto-grants-2011_08 |