HRID1678310

反应详情

EQUATION

反应方程式

HRID 1678310 的结构方程式

AUXILIARIES

试剂、催化剂与溶剂

1

PROCEDURE

实验过程

A solution of 6-fluoro-2-methylquinoline-4-carboxylic acid (500 mg) and PCl5 (500 mg) in dichloromethane (10 mL) was refluxed for half an hour. Then dichloromethane and POCl3 were removed under reduced pressure to give 6-fluoro-2-methylquinoline-4-carbonyl chloride.

WORKUP

后处理

  1. customThen dichloromethane and POCl3 were removed under reduced pressure