反应详情

5′-tert-Butoxycarbonylamino-2′-methyl-biphenyl-4-carboxylic acid ethyl ester (6.6 g) was stirred in ethanol (120 ml) and 6M HCl (50 ml) at 20 C for 2 days. The ethanol was evaporated and the residue basified and then extracted with dichloromethane. The dried extracts were evaporated giving the title compound as a pale brown crystalline solid (4 g).

1. customThe ethanol was evaporated
2. extractionextracted with dichloromethane
3. customThe dried extracts were evaporated