Hydrochloric Acid → HCID 67372184, compound

Participants

Reaction Steps

2′-Methoxy-5′-nitro-biphenyl-4-carboxylic acid ethyl ester (600 mg) in ethanol 90 ml) and 2M HCl (2.5 ml) was hydrogenated at RTP for 3 h. The mixture was then filtered through celite and the solvent evaporated. The dark solid residue was dissolved in 1:1 aqueous acetonitrile, filtered through celite again and evaporated giving the title compound as a red solid (595 mg).

Provenance & Evidence