HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 59822356, compound → HCID 59822333, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 59822356 | HCID 59822356 | — |
| Catalyst | HCID 178418406 | HCID 178418406 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 59822333 | HCID 59822333 | 96.4% |
Reaction Steps
5′-Hydroxymethyl-2′-methyl-biphenyl-4-carboxylic acid [4-(1,1-dioxo-1lambda*6*-thiomorpholin-4-ylmethyl)-phenyl]-amide (500 mg) in dichloromethane (30 ml) was treated with manganese dioxide (3 g) and the mixture stirred at 20 C for 18 h. The suspension was then filtered through celite and the mother liquor evaporated giving the title compound as a colourless oil (480 mg)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08008303B2 |
| Source dataset | uspto-grants-2011_08 |
| ORD ID | ord-da28510bcbf54691a54689ca437c1c4d |
| Source note | uspto-grants-2011_08 |