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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1678491Generated: November 1, 2026

HCID 59822356, compound → HCID 59822333, compound

https://huagongshe.com/reaction/1678491

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 59822356HCID 59822356—
CatalystHCID 178418406HCID 178418406—
SolventDichloromethaneHCID 6344—
ProductHCID 59822333HCID 5982233396.4%

Reaction Steps

5′-Hydroxymethyl-2′-methyl-biphenyl-4-carboxylic acid [4-(1,1-dioxo-1lambda*6*-thiomorpholin-4-ylmethyl)-phenyl]-amide (500 mg) in dichloromethane (30 ml) was treated with manganese dioxide (3 g) and the mixture stirred at 20 C for 18 h. The suspension was then filtered through celite and the mother liquor evaporated giving the title compound as a colourless oil (480 mg)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08008303B2
Source datasetuspto-grants-2011_08
ORD IDord-da28510bcbf54691a54689ca437c1c4d
Source noteuspto-grants-2011_08