HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Nitro-4-(trifluoromethoxy)benzoic acid → 3-Amino-4-(trifluoromethoxy)benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Nitro-4-(trifluoromethoxy)benzoic acid | HCID 18626217 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 3-Amino-4-(trifluoromethoxy)benzoic acid | HCID 20274094 | 97.7% |
Reaction Steps
A solution of 3-nitro-4-trifluoromethoxybenzoic acid (3 g) in methanol (240 ml) was hydrogenated at 50° C. and 50 bar using H-cube apparatus. The methanol solution was evaporated giving the title compound as a white solid (2.58 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08008303B2 |
| Source dataset | uspto-grants-2011_08 |
| ORD ID | ord-ebfd23b88677408e80c4208b95b8ebd6 |
| Source note | uspto-grants-2011_08 |