Hydrochloric Acid → HCID 13941271, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of [3-(methoxymethoxy)-5-phenoxyphenyl]methanol (0.75 g, 2.86 mmol) in ethanol (10 mL) was added concentrated hydrochloric acid (1 mL), and the mixture was stirred at 40° C. for 4 hours. The reaction solution was concentrated under reduced pressure, and the resulting residue was purified with silica gel column chromatography (hexane/ethyl acetate=5:5) to give the title compound (0.60 g, yield 96%) as an oily matter.

Provenance & Evidence