HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 67375153, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 23136537 | HCID 23136537 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 67375153 | HCID 67375153 | 89% |
Reaction Steps
To 3-{4-[(3-{2-[(tert-butoxycarbonyl)amino]ethoxy}-5-phenoxybenzyl)oxy]-3-fluorophenyl}propanoic acid (0.20 g, 0.38 mmol) was added a solution of hydrochloric acid in ethyl acetate (4 N, 1 mL), and the mixture was stirred 15 hours. The reaction solution was concentrated under reduced pressure, and the resulting white powders were separated by filtration, washed with ethyl acetate and dried to give the title compound. Yield 89%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08008525B2 |
| Source dataset | uspto-grants-2011_08 |
| ORD ID | ord-4ff42f00d85a4ed797e2fc5259a12d87 |
| Source note | uspto-grants-2011_08 |