Sodium Hydroxide → [2-(4-Chloro-phenyl)-4,5,6,7-tetrahydro-2H-indazol-3-yl]-cyclohexyl-acetic acid

Participants

Role	Name	HCID	Charge
Reactant	Sodium Hydroxide	HCID 14798	—
Reactant	[2-(4-Chloro-phenyl)-4,5,6,7-tetrahydro-2H-indazol-3-yl]-cyclohexyl-acetic acid ethyl ester	HCID 67131110	—
Solvent	Methanol	HCID 887	—
Product	[2-(4-Chloro-phenyl)-4,5,6,7-tetrahydro-2H-indazol-3-yl]-cyclohexyl-acetic acid	HCID 67131112	—

Reaction Steps

In analogy to the procedure described in example 4.5, [2-(4-chloro-phenyl)-4,5,6,7-tetrahydro-2H-indazol-3-yl]-cyclohexyl-acetic acid ethyl ester (example 4.3) was treated with aqueous NaOH solution in MeOH to give the title compound as yellow foam which was sufficiently pure to be used in the next step. MS: m/e=373.2 [M+H+].

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08008505B2
Source dataset	uspto-grants-2011_08
ORD ID	ord-9bae19ce1ddc42bfae546ad950289937
Source note	uspto-grants-2011_08