Potassium tert-butoxide → HCID 67130964, compound

HRID 1678642Notes

Reaction equation

HRID 1678642 reaction equation
[C:1]([O:5][C:6](=[O:22])[CH:7]([O:11][C:12]1[CH:17]=[CH:16][C:15]([N+:18]([O-:20])=[O:19])=[C:14]([F:21])[CH:13]=1)[CH2:8][CH2:9]Br)([CH3:4])([CH3:3])[CH3:2].CC(C)([O-])C.[K+]>C1COCC1>[C:1]([O:5][C:6]([C:7]1([O:11][C:12]2[CH:17]=[CH:16][C:15]([N+:18]([O-:20])=[O:19])=[C:14]([F:21])[CH:13]=2)[CH2:9][CH2:8]1)=[O:22])([CH3:4])([CH3:3])[CH3:2]

Participants

4

Reactant 2

HCID 23665647Potassium tert-butoxideHCID 67131258HCID 67131258, compound

Product 1

HCID 67130964HCID 67130964, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

In analogy to the procedure described in example 15.2, 4-bromo-2-(3-fluoro-4-nitro-phenoxy)-butyric acid tert-butyl ester was treated with potassium tert-butoxide in THF to afford the title compound as a brown solid. MS: m/e=298.3 [M+H+].

Sources & evidence

ORD record
ord-5115fc9d4a25402285a0412cb8eabe22
Source dataset
uspto-grants-2011_08
Patent number
US08008505B2

Reaction notes

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