反应详情

In analogy to the procedure described in example 6, [rac]-[2-(4-chloro-phenyl)-5,6-difluoro-2H-indazol-3-yl]-cyclohexyl-acetic acid (example 24.7) was converted into the corresponding acid chloride with thionyl chloride which subsequently reacted with 2-(4-amino-3-fluoro-phenoxy)-2-methyl-propionic acid ethyl ester in the presence of DMAP to give the title compound as brown solid. MS: m/e=628.3 [M+H+].