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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1678656Generated: October 30, 2026

Lithium Hydroxide → HCID 67131223, compound

https://huagongshe.com/reaction/1678656

Reaction equation

Participants

RoleNameHCIDCharge
ReactantLithium HydroxideHCID 3939—
ReactantHCID 67131002HCID 67131002—
SolventMethanolHCID 887—
SolventTetrahydrofuranHCID 8028—
ProductHCID 67131223HCID 67131223—

Reaction Steps

In analogy to the procedure described in example 7.2, [rac]-4-{[2-(4-chloro-phenyl)-5,6-difluoro-2H-indazol-3-yl]-cyclohexyl-methoxymethyl}-benzoic acid ethyl ester was treated with 1 N aqueous lithium hydroxide solution in THF and MeOH to give the title compound as colorless foam. MS: m/e=511.3 [M+H+].

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08008505B2
Source datasetuspto-grants-2011_08
ORD IDord-be4f576a73424e099af1f170a0a3a96d
Source noteuspto-grants-2011_08