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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1678679Generated: October 31, 2026

Lithium Hydroxide → HCID 45111802, compound

https://huagongshe.com/reaction/1678679

Reaction equation

Participants

RoleNameHCIDCharge
ReactantLithium HydroxideHCID 3939—
Reactant[Rac]-1-(4-{2-[2-(4-chloro-phenyl)-2h-indazol-3-yl]-2-cyclohexyl-ethoxy}-phenoxy)-cyclopropanecarboxylic acid methyl esterHCID 45111663—
SolventMethanolHCID 887—
SolventTetrahydrofuranHCID 8028—
ProductHCID 45111802HCID 45111802—

Reaction Steps

In analogy to the procedure described in example 7.2, [rac]-1-(4-{2-[2-(4-chloro-phenyl)-2H-indazol-3-yl]-2-cyclohexyl-ethoxy}-phenoxy)-cyclopropanecarboxylic acid methyl ester was treated with 1 N aqueous lithium hydroxide solution in THF and MeOH to give the title compound as yellow oil. MS: m/e=533.2 [M−H−].

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08008505B2
Source datasetuspto-grants-2011_08
ORD IDord-cb9ce45a7c6947ae896d343261af6218
Source noteuspto-grants-2011_08