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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1678681Generated: November 2, 2026

Lithium Hydroxide → HCID 45111803, compound

https://huagongshe.com/reaction/1678681

Reaction equation

Participants

RoleNameHCIDCharge
ReactantLithium HydroxideHCID 3939—
ReactantHCID 67131159HCID 67131159—
SolventMethanolHCID 887—
SolventTetrahydrofuranHCID 8028—
ProductHCID 45111803HCID 45111803—

Reaction Steps

In analogy to the procedure described in example 7.2, [rac]-1-(4-{[2-(4-chloro-phenyl)-5,6-difluoro-2H-indazol-3-yl]-cyclohexyl-methoxy}-phenoxy)-cyclopropanecarboxylic acid methyl ester was treated with 1 N aqueous lithium hydroxide solution in THF and MeOH to give the title compound as colorless liquid. MS: m/e=553.3 [M+H+].

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08008505B2
Source datasetuspto-grants-2011_08
ORD IDord-41d9c63d5f744392bbbe408140643107
Source noteuspto-grants-2011_08