反应详情

39 gms. of hydrazine are dissolved in 500 ml. of n-propanol and 105 gms. of 1,3-dimethyl-4-nitro-5-chloro-1H-pyrazole dissolved in propanol are added dropwise at 100°. The reaction mixture is then refluxed for 4 hours. On cooling, 5-hydrazino-1,3-dimethyl-4-nitro-1H-pyrazole crystallizes in the form of yellow needles. By concentrating the mother liquor an additional quantity of product is obtained. The combined crude is recrystallized from propanol, yield 98 gms. of yellow needles, m.p. 177°-179°.

1. additionare added dropwise at 100°
2. temperatureThe reaction mixture is then refluxed for 4 hours
3. temperatureOn cooling
4. custom5-hydrazino-1,3-dimethyl-4-nitro-1H-pyrazole crystallizes in the form of yellow needles
5. concentrationBy concentrating the mother liquor an additional quantity of product
6. customis obtained
7. customis recrystallized from propanol, yield 98 gms