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HRID1678851

反应详情

EQUATION

反应方程式

HRID 1678851 的结构方程式

REACTANTS

反应物

2
结构：CC[O-].[Na+]
HCID2723922

Ethanol, sodium salt

C2H5NaO

结构：CCOC(=O)c1cnn2c1c(Cl)nc1c(C)nn(C)c12
HCID53966407

未命名化合物

PRODUCTS

生成物

1
结构：CCOC(=O)c1cnn2c1c(OCC)nc1c(C)nn(C)c12
HCID131711039

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CCO
溶剂HCID702

Ethanol

C2H6O

PROCEDURE

实验过程

5.86 gms. of 5-chloro-1,3-dimethyl-1H-dipyrazolo[1,5-a:4',3'-e]pyrazine-6-carboxylic acid, ethyl ester, in ethanol is refluxed with 20 mM of sodium ethylate for 30 minutes. Upon cooling, the product, 5-ethoxy-1,3-dimethyl-1H-dipyrazolo[1,5-a:4',3'-e]pyrazine-6-carboxylic acid, ethyl ester, crystallizes in the form of white needles. The product is recrystallized from n-propanol, yield 4.2 gms, m.p. 116°-118°.

WORKUP

后处理

  1. temperatureUpon cooling
  2. customthe product, 5-ethoxy-1,3-dimethyl-1H-dipyrazolo[1,5-a:4',3'-e]pyrazine-6-carboxylic acid, ethyl ester, crystallizes in the form of white needles
  3. customThe product is recrystallized from n-propanol, yield 4.2 gms, m.p. 116°-118°